Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.
What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?
Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.
At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 75 |
Director, Regulatory Affairs (U.S. Advertising and Promotion)
Cambridge, Massachusetts
Overview The Director, Regulatory Affairs for U.S. Advertising and Promotion (USAP) will provide strategic regulatory advice to internal stakeholders regarding tactics and communications related to Alnylam's marketed products, investigation...
7h
| Job Type | Full Time |
Senior Manager, Regulatory Project Management
Cambridge, Massachusetts
Overview The Senior Manager of Regulatory Project Management will report to the Sr. Director of Regulatory Technology and Operations. Given Alnylam's uniquely robust pipeline, a need has been identified to establish a focused capability to ...
13h
| Job Type | Full Time |
Scientist, Targeted Delivery (Receptor Identification)
Cambridge, Massachusetts
Overview The Research Department at Alnylam is seeking a Scientist to join a growing team responsible for advancing RNAi therapeutics into the future, by opening up targeted delivery to all tissues. The successful candidate will have a work...
1d
| Job Type | Full Time |
Senior Director, TTR Global Marketing
Cambridge, Massachusetts
Overview We are seeking a visionary Global Senior Director to continue the momentum for the global launch of our flagship AMVUTTRA brand in a highly competitive ATTR-CM market. This critical role will refine our global positioning strategy ...
2d
| Job Type | Full Time |
Senior Associate Scientist, Bioinformatics
Cambridge, Massachusetts
Overview: With six commercially approved RNAi therapeutics, Alnylam is at the forefront of gene silencing. Our success is built upon a rational, sequence-based approach to drug design driven by predictive models and high-throughput data gen...
3d
| Job Type | Full Time |
Senior Director, Manufacturing, CMC & Supply Chain Technology
Cambridge, Massachusetts
Overview: Alnylam is seeking a strategic and pragmatic IT leader to serve as Sr. Director, Manufacturing, CMC & Supply Chain Technology. This role will own the end-to-end digital strategy, operations, and application lifecycle across Manufa...
3d
| Job Type | Full Time |
Principal Scientist, Target Validation and Translational Research
Cambridge, Massachusetts
Overview: The Research Department at Alnylam is seeking an experienced Principal Scientist to join an interdisciplinary team dedicated to broaden our oligonucleotide platform and extrahepatic delivery. The ideal candidate will have expertis...
7d
| Job Type | Full Time |
Senior Associate Scientist, Process Sciences
Cambridge, Massachusetts
Overview: The successful candidate will be a part of the Process Science group, responsible for process development, in-house non-GMP manufacturing, report and protocol authoring and reviewing, process transfer to CMOs, and stage 1 manufact...
7d
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: The Director, Process Sciences will be responsible for process development, optimization, scale-up and process characterization of drug candidates for platform delivery of oligonucleotide APIs. The candidate will work closely with...
7d
| Job Type | Full Time |
Senior Director, Clinical Portfolio Technology
Cambridge, Massachusetts
Overview: Alnylam seeks a strategic technology leader to drive the strategy, delivery, and governance of platforms supporting Clinical Delivery, Portfolio Management, and Data Science, Statistics, & Epidemiology (DSSE). This role translates...
7d
| Job Type | Full Time |