Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 170 |
Director, Market Research - Value Pipeline Commercialization (VPC)
Cambridge, Massachusetts
Overview: Alnylam is seeking a Director of Market Research to support the Value Pipeline Commercialization (VPC) organization across the full pipeline, from preclinical through Phase 3, spanning multiple therapeutic areas and potential busi...
12h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: We are seeking a highly skilled and experienced Executive Assistant to provide consistent, high-level administrative support to the Human Resources (HR) organization. This role requires a proactive, detail-oriented professional wh...
19h
| Job Type | Full Time |
Director, New Product Commercialization, CNS
Cambridge, Massachusetts
Overview We are seeking a strategic, forward-thinking leader to join our team in a newly created Product Planning role. This individual will play a critical role in shaping the long-term commercial vision of our pipeline assets-integrating ...
19h
| Job Type | Full Time |
Director, Clinical Research-Cardiology
Cambridge, Massachusetts
Overview Alnylam Pharmaceuticals is seeking an imaginative physician drug developer, with the flexibility and confidence to work in therapeutic areas that may be beyond their particular expertise or experience. This is an opportunity to pro...
19h
| Job Type | Full Time |
Vice President, Global Trial Optimization
Cambridge, Massachusetts
Overview The Vice President, Global Trial Optimization leads strategic feasibility, protocol optimization, and scenario planning to inform clinical trial design that aligns the science with data driven, efficient delivery plans. Also, the V...
19h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview Alnylam Pharmaceuticals is looking for an Internal Audit Manager to be a key contributing member of the Internal Audit function for one of Cambridge's most innovative, publicly traded biotech companies, focused on translating the s...
19h
| Job Type | Full Time |
Vice President, Pipeline Delivery Systems & Process Enablement
Cambridge, Massachusetts
Overview Pipeline Delivery Systems & Process Enablement is a strategic leadership role responsible for building and scaling a seamless, integrated ecosystem of systems, data, and operational processes that enable efficient and predictable d...
19h
| Job Type | Full Time |
Manager, Manufacturing Operations
Cambridge, Massachusetts
Overview The Manager, Manufacturing Operations is an integral part of the Norton Internal Manufacturing team. This role will initially be involved in the start-up of Norton's new commercial Drug Substance manufacturing train, including supp...
1d
| Job Type | Full Time |
Director, New Product Planning & BD Support
Cambridge, Massachusetts
Overview: We are seeking a strategic, forward-thinking leader to join our team in a newly created role that is accountable for conducting assessment of both internal and external asset opportunities. This individual will be accountable to i...
1d
| Job Type | Full Time |
Associate Scientist II, Biology
Cambridge, Massachusetts
Overview The CNS Research Group at Alnylam is seeking a self-driven Associate Scientist II with expertise in tissue analysis, sample management and automation to join our innovative, fast faced, and interdisciplinary team. We particularly s...
2d
| Job Type | Full Time |